The efficacy of pregabalin for acute pain control in herpetic neuralgia patients

@article{Wang2017TheEO,
  title={The efficacy of pregabalin for acute pain control in herpetic neuralgia patients},
  author={Suo-liang Wang and Hua Wang and Hui-yong Nie and Gang Bu and Xi Shen and Hui Wang},
  journal={Medicine},
  year={2017},
  volume={96}
}
Objective: This meta-analysis aimed to illustrate the efficacy and safety of preganalin for pain management in patients with postherpetic neuralgia (PHN). Methods: In July 2017, a systematic computer-based search was conducted in PubMed, EMBASE, Web of Science, Cochrane Database of Systematic Reviews, and Google database. Data on patients with PHN that compared pregabalin versus placebo were retrieved. The endpoints were the visual analog scale (VAS) at 8 weeks, the percentage of 30% and 50… 
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13 Citations

COMPARISON OF PREGABALIN AND NORTRIPTYLINE ON EFFICACY AND SAFETY IN POSTHERPETIC NEURALGIA
TLDR
Both pregabalin and nortriptyline were effective in patients of PHN, but pre gabalin was found to be better than nortriptYline at 8 weeks, and both drugs were well tolerated, though preg abalin had lesser number of ADRs.
Benefits and harms of pregabalin in the management of neuropathic pain: a rapid review and meta-analysis of randomised clinical trials
TLDR
Pregabalin has beneficial effects on some symptoms of neuropathic pain, however, its use significantly increases the risk of a number of adverse events and discontinuation due to adverse events.
Topical Lidocaine Medicated Plaster 5% and Pregabalin for the Treatment of Post-Herpetic Neuralgia: A Systematic Review and Meta-Analysis
  • Hassan A. Moria
  • Medicine
    Journal of Pharmaceutical Research International
  • 2022
TLDR
Five % lidocaine medicated plaster was effective for the treatment of post-herpetic neuralgia and was more beneficial than placebo and pregabalin.
Oral pharmacotherapeutics for the management of peripheral neuropathic pain conditions – a review of clinical trials
TLDR
This narrative review presents the results of different prospective, randomized controlled trials, systematic reviews and meta-analyses assessing the effects of different oral medications in the management of various peripheral neuropathic pain conditions and concludes that none of them were significantly superior.
Ultrasound-guided Pulsed Radiofrequency in the Management of Thoracic Postherpetic Neuralgia: A Randomized, Double-blinded, Controlled Trial
TLDR
Ultrasound-guided PRF for ICNs in combination with pharmacotherapy seems to be a safe and effective treatment modality for postherpetic neuralgia.
Preemptive pregabalin for postoperative analgesia during minimally invasive hysterectomy: a systematic review and meta-analysis of randomized controlled trials
TLDR
Compared with placebo, preemptive pregabalin was largely safe, and was correlated with superior analgesic effects in terms of lower postoperative pain scores and higher opioid-sparing effects.
Efficacy and Safety of the Controlled-release Pregabalin Tablet (GLA5PR GLARS-NF1) and Immediate-release Pregabalin Capsule for Peripheral Neuropathic Pain: a Multicenter, Randomized, Double-blind, Parallel-group, Active-controlled, Phase III Clinical Trial.
[S2k guideline for the diagnosis and therapy of zoster and post-zoster neuralgia].
TLDR
This guideline provides an overview of clinical and molecular diagnostics as well as antigen detection, antibody culture and viral culture and the antiviral therapy of zoster and postzoster neuralgia.
Topical gabapentin gel alleviates allodynia and hyperalgesia in the chronic sciatic nerve constriction injury neuropathic pain model
TLDR
A topical gabapentin dermal application was examined in the chronic constriction injury (CCI) model of neuropathic pain to curtail side‐effects.
S2k‐Leitlinie zur Diagnostik und Therapie des Zoster und der Postzosterneuralgie
  • G. Gross, Lisa Eisert, A. Nast
  • Medicine
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • 2020
TLDR
Die Leitlinie wurde im formellen Konsensusverfahren (S2k) von Dermatologen, Virologen/Infektiologicen, Ophthalmologisten, HNO‐Ärzten, Neurologen, Pädiatern and Anästhesisten/Schmerzmedizinern erstellt.
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Post-herpetic neuralgia (PHN) is a chronic neuropathic pain condition that persists 3 months or more following an outbreak of shingles. Shingles, also known as acute herpes zoster, is associated with…
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