The efficacy of once-daily fluticasone furoate/vilanterol in asthma is comparable with morning or evening dosing.

@article{Kempsford2013TheEO,
  title={The efficacy of once-daily fluticasone furoate/vilanterol in asthma is comparable with morning or evening dosing.},
  author={Rodger D Kempsford and Amanda J. Oliver and Joanne Bal and Lee Tombs and Dean Quinn},
  journal={Respiratory medicine},
  year={2013},
  volume={107 12},
  pages={1873-80}
}
AIM To investigate the effect of time of day of dosing (morning or evening) on lung function following administration of fluticasone furoate (FF)/vilanterol (VI) 100/25 mcg. METHODS Double-blind, placebo-controlled, randomised, three-way crossover study. Subjects with persistent asthma (N = 26) received FF/VI (morning or evening) or matching placebo once-daily for 14 (± 2 days) via dry powder inhaler (DPI). Weighted mean (0-24h) and pre-treatment FEV1 (morning and evening) were determined… CONTINUE READING
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