The efficacy of morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia is different from that on neuroma pain in the rat neuropathic pain model.

@article{Miyazaki2012TheEO,
  title={The efficacy of morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia is different from that on neuroma pain in the rat neuropathic pain model.},
  author={Rika Miyazaki and Tatsuo Yamamoto},
  journal={Anesthesia and analgesia},
  year={2012},
  volume={115 1},
  pages={182-8}
}
BACKGROUND It has been reported that <50% of neuropathic pain patients are satisfactorily treated with drugs. It is possible that this lack of efficacy of drugs on neuropathic pain might be due to the drugs prescribed, regardless of the origin of pain. We compared the efficacy of orally administered morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia with that on neuroma pain using the tibial neuroma transposition (TNT) model. METHODS In the TNT model, the tibial nerve is… CONTINUE READING

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