The efficacy of local infiltration analgesia in the early postoperative period after total knee arthroplasty: A systematic review and meta-analysis

@article{Seangleulur2016TheEO,
  title={The efficacy of local infiltration analgesia in the early postoperative period after total knee arthroplasty: A systematic review and meta-analysis},
  author={Alisa Seangleulur and Pramook Vanasbodeekul and Sunisa Prapaitrakool and Sukhumakorn Worathongchai and Thunyarat Anothaisintawee and Mark A McEvoy and Pascal-Andr{\'e} Vendittoli and John Richard Attia and Ammarin Thakkinstian},
  journal={European Journal of Anaesthesiology},
  year={2016},
  volume={33},
  pages={816–831}
}
BACKGROUND Local infiltration analgesia (LIA) has emerged as an alternative treatment for postoperative pain after total knee arthroplasty (TKA). Its efficacy remains inconclusive with inconsistent results from previous studies and meta-analyses. There is no agreement on which local anaesthetic agent and infiltration technique is most effective and well tolerated. OBJECTIVE The objective was to compare LIA after primary TKA with placebo or no infiltration in terms of early postoperative pain… Expand
THE ANALGESIC EFFICACY OF A STANDARDIZED LOCAL INFILTRATION ANALGESIA TECHNIQUE OVER EQUIVALENT EPIDURAL ANALGESIA IN TOTAL KNEE ARTHROPLASTY AND A COMPARATIVE ANALYSIS WITH MOST CITED RCTs
TLDR
The multimodal local infiltration analgesia offers better pain relief, ROM and earlier mobilization than epidural analgesia if consistently standartized, facilitating rehabilitation and early return to day to day activities with lesser side effects and no transient peroneal nerve palsy if used methodically. Expand
Comparison of Periarticular Injection and Intra-articular Injection for Pain Management After Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.
  • W. Deng, Jie Chen, +4 authors Deliang Qiu
  • Medicine
  • Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses
  • 2021
TLDR
Based on the available evidence, PAI does not offer superior effects at pain control and discharge than IAI after TKA, and further large well-designed randomized controlled trials are still needed to validate this conclusion. Expand
Local anesthetic infusion pump for pain management following total knee arthroplasty: a meta-analysis
TLDR
A systematic review and meta-analysis of randomized controlled trials of patients prepared for primary TKA found no evidence to support the routine use of local anesthetic infusion pump in the management of acute pain following total knee arthroplasty. Expand
Post-operative pain management using local infiltration analgesia (LIA) in total knee arthroplasty (TKA): A prospective study
TLDR
Local Infiltration Analgesia is a safe, simple and efficient method of reducing postoperative pain after total knee arthroplasty (TKA) which facilitates early rehabilitation among the patients and has an overall improvement in patient satisfaction with the procedure. Expand
Local infiltration analgesia in primary total knee arthroplasty.
TLDR
Intra-operative single-dose LIA can effectively reduce postoperative pain, morphine demand, and morphine consumption in TKA, and the use of LIA is recommended during TKA. Expand
Additional benefit of local infiltration of analgesia to femoral nerve block in total knee arthroplasty: double-blind randomized control study
TLDR
The addition of local infiltration of analgesia to femoral nerve block promoted post-operative pain relief and the recovery of knee ROM in the early post-operatively period and is an effective method for post- operative pain management after TKA. Expand
Comparison between local infiltration analgesia with combined femoral and sciatic nerve block for pain management after total knee arthroplasty
TLDR
Local infiltration analgesia provided a similar analgesic effect and complications compared with combined femoral and sciatic nerve block in the short term, and provided better postoperative analgesia than either PNB or LIA. Expand
Opioid-Free Total Knee Arthroplasty? Local Infiltration Analgesia Plus Multimodal Blood-Loss Prevention Make it Possible
TLDR
Post-operative pain management protocols vary so much that it is difficult to strongly favor a determined pathway, and Multimodal blood-loss prevention is sometimes recommended in combination with opioid-free analgesia, however, no differences are reported or contradictory results exist. Expand
Analgesic efficacy of infiltration between the popliteal artery and capsule of the knee (iPACK) block added to local infiltration analgesia and continuous adductor canal block after total knee arthroplasty: a randomized clinical trial
TLDR
The addition of an iPACK block to the LIA and CACB does not reduce the postoperative opioid consumption nor improve analgesia, however, it may improve immediate functional performance and reduce the length of hospitalization after TKA. Expand
Adductor canal block combined with local infiltration analgesia versus isolated adductor canal block in reducing pain and opioid consumption after total knee arthroplasty: a systematic review and meta-analysis
TLDR
ACB plus LIA significantly reduced the postoperative pain score on POD 0 and POD 1 compared with isolated ACB and was associated with a significant reduction in opioid consumption during the early postoperative period. Expand
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Local infiltration analgesia following total knee arthroplasty: effect on post-operative pain and opioid consumption—a meta-analysis
TLDR
LIA might be able to decrease pain and the use of opioids on the first post-operative day following TKA, however, due to the high level of heterogeneity between the studies, no firm conclusions can be drawn. Expand
Analgesic efficacy of local infiltration analgesia in hip and knee arthroplasty: a systematic review.
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Overall, LIA provides effective analgesia in the initial postoperative period after TKA in most randomized clinical trials even when combined with multimodal systemic analgesia. Expand
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TLDR
The current evidence shows that the use of single-dose LIA is effective for postoperative pain management in TKA patients, with satisfactory short-term safety, and more high-quality RCTs with long-term follow-ups are required for examining the long- term safety. Expand
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Patients receiving local anaesthetic infiltration after total hip replacement and total knee replacement had reduced opioid consumption, earlier mobilisation, and lower incidence of vomiting, and fewer days in hospital after THR and TKR. Expand
Local Infiltration Analgesia Versus Intrathecal Morphine for Postoperative Pain Management After Total Knee Arthroplasty: A Randomized Controlled Trial
TLDR
LIA technique provided better postoperative analgesia and earlier mobilization, resulting in shorter hospital stay, than did intrathecal morphine after TKA, and patient satisfaction was greater in group L than in group M. Expand
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TLDR
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Single periarticular local infiltration analgesia reduces opiate consumption until 48 hours after total knee arthroplasty
TLDR
Single periarticular infiltration reduced the amount of oxycodone used and enabled adequate pain management in conjunction with standardized peroral medication without adverse effects in patients undergoing unilateral total knee arthroplasty. Expand
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TLDR
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Comparison of patient outcomes in periarticular and intraarticular local anaesthetic infiltration techniques in total knee arthroplasty
TLDR
This study is the first of its kind to directly compare a periarticular to intraarticular injection technique when using local infiltration analgesia for total knee arthroplasty, and shows no clear statistically significant benefit with either technique. Expand
Effect of Single-Injection versus Continuous Local Infiltration Analgesia after Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Study
TLDR
CLIA provided prolonged superior analgesia and was associated with more favourable functional recovery and patient satisfaction compared with SLIA, and the CLIA group had significantly lower consumption of morphine compared with the SLIA group. Expand
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