The efficacy of individual-donation and minipool testing to detect low-level hepatitis B virus DNA in Taiwan.

@article{Yang2010TheEO,
  title={The efficacy of individual-donation and minipool testing to detect low-level hepatitis B virus DNA in Taiwan.},
  author={M H Yang and Lei Li and Ying-Shen Hung and Cheng-Shen Hung and J Y Allain and K C Lin and S J L Tsai},
  journal={Transfusion},
  year={2010},
  volume={50 1},
  pages={65-74}
}
BACKGROUND Financial constraints are the main concern in implementing nucleic acid testing (NAT) as routine blood screening in Taiwan. The PROCLEIX ULTRIO assay (Ultrio) on the TIGRIS System (Novartis Diagnostics) was evaluated for its operational performance both for individual-donation testing (IDT) and in minipools of 4 (MP4) to develop a feasible solution. STUDY DESIGN AND METHODS Analytical sensitivity was determined by testing WHO international standards. We tested 10,290 blood donors… CONTINUE READING
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