The efficacy of early versus delayed P2Y12 inhibition in percutaneous coronary intervention for ST-elevation myocardial infarction: a systematic review and meta-analysis.

@article{BellemainAppaix2018TheEO,
  title={The efficacy of early versus delayed P2Y12 inhibition in percutaneous coronary intervention for ST-elevation myocardial infarction: a systematic review and meta-analysis.},
  author={A. Bellemain-Appaix and C{\'e}line B{\'e}gu{\'e} and Deepak L. Bhatt and K. Ducci and R. Harrington and M. Roe and S. Wiviott and M. Cucherat and J. Silvain and J. Collet and F. Bernasconi and G. Montalescot},
  journal={EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology},
  year={2018},
  volume={14 1},
  pages={
          78-85
        }
}
AIMS The aim of this meta-analysis was to compare the benefit of "early" vs. "delayed" P2Y12 inhibition in patients undergoing percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). METHODS AND RESULTS We conducted a meta-analysis including seven randomised controlled trials (RCTs) which compared early vs. delayed P2Y12inhibition in STEMI patients scheduled for PCI, providing data on major adverse cardiac events (MACE), all-cause death, and major bleeding… Expand
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