The efficacy of continuous local arterial infusion of 5-fluorouracil and cisplatin through an implanted reservoir for severe advanced hepatocellular carcinoma.

@article{Toyoda1995TheEO,
  title={The efficacy of continuous local arterial infusion of 5-fluorouracil and cisplatin through an implanted reservoir for severe advanced hepatocellular carcinoma.},
  author={Hidenori Toyoda and S. Hidaka Z. Hu H. Kato K. Nakano and Takashi Kumada and Isao Takeda and Kazuhiko Sugiyama and Tadahiro Osada and Seiki Kiriyama and Tatsuo Suga and Masamitsu Takahashi},
  journal={Oncology},
  year={1995},
  volume={52 4},
  pages={
          295-9
        }
}
There is not yet an effective standard therapy for severe advanced hepatocellular carcinoma (HCC). We attempted continuous local arterial infusion chemotherapy using 5-fluorouracil (5-FU) and cisplatin (CDDP) with an implanted reservoir for these patients, and evaluated its efficacy. Twenty-one HCC patients received continuous arterial infusion of 5-FU and CDDP for 1 week, followed by a 1-week no-infusion period; this regimen was repeated 1-32 times, and patients were observed for 36-549 days… CONTINUE READING
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