The efficacy of cevimeline hydrochloride in the treatment of xerostomia in Sjögren’s syndrome in southern Chinese patients: a randomised double-blind, placebo-controlled crossover study

@article{Leung2007TheEO,
  title={The efficacy of cevimeline hydrochloride in the treatment of xerostomia in Sj{\"o}gren’s syndrome in southern Chinese patients: a randomised double-blind, placebo-controlled crossover study},
  author={Kwong Chuen Leung and Anne Sinclair McMillan and Michael M. C. Wong and Winifred K Leung and M Y Mok and C S Lau},
  journal={Clinical Rheumatology},
  year={2007},
  volume={27},
  pages={429-436}
}
Cevimeline hydrochloride, a specific agonist of the M3 muscarinic receptor, is beneficial in the treatment of symptoms of xerostomia and xerophthalmia associated with Sjögren’s syndrome (SS). Cevimeline has not been evaluated in southern Chinese patients. Furthermore, the effects of cevimeline on health-related quality of life and oral health status are not known. In this randomised, double-blind, placebo-controlled crossover study, patients received cevimeline 30 mg or matched placebo three… CONTINUE READING
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