The efficacy of amlexanox OraDisc on the prevention of recurrent minor aphthous ulceration.

@article{Murray2006TheEO,
  title={The efficacy of amlexanox OraDisc on the prevention of recurrent minor aphthous ulceration.},
  author={Brenda Murray and Paul A Biagioni and P J Lamey},
  journal={Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology},
  year={2006},
  volume={35 2},
  pages={117-22}
}
BACKGROUND The study was designed to determine the efficacy of OraDisc (active component 2 mg amlexanox) on the prevention of aphthous ulcers treated at the prodromal stage. METHODS Thermographic imaging was used to confirm the presence of a prodromal ulcer. Fifty-two patients were randomized to receive OraDisc (N = 26) or vehicle patches (N = 26). Patches were applied four times a day for 72 h over the prodromal area. The percentage of subjects who developed an ulcer at 72 h was compared… CONTINUE READING

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