The efficacy of amantadine and other antiviral compounds against two salmonid viruses in vitro.

@article{Hudson1988TheEO,
  title={The efficacy of amantadine and other antiviral compounds against two salmonid viruses in vitro.},
  author={James Bradley Hudson and Evarts A. Graham and Michael M. Simpson},
  journal={Antiviral research},
  year={1988},
  volume={9 6},
  pages={379-85}
}
Various compounds, with known clinical efficacy against human viruses, were evaluated for their ability to inhibit the growth of infectious hematopoietic necrosis virus (IHNV, a rhabdovirus), and infectious pancreatic necrosis virus (IPNV, a birnavirus), in rainbow trout cell cultures. Amantadine inhibited the plaque forming ability of IHNV, at concentrations which did not affect cell growth or morphology, although it was not active against IPNV. Metisazone and bis-benzimidazole were also… CONTINUE READING

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