The efficacy of TonoLab in detecting physiological and pharmacological changes of mouse intraocular pressure--comparison with TonoPen and microneedle manometery.

@article{Saeki2008TheEO,
  title={The efficacy of TonoLab in detecting physiological and pharmacological changes of mouse intraocular pressure--comparison with TonoPen and microneedle manometery.},
  author={Tadashiro Saeki and Makoto Aihara and Masaaki Ohashi and Makoto Araie},
  journal={Current eye research},
  year={2008},
  volume={33 3},
  pages={247-52}
}
PURPOSE The efficacy of two non-invasive tonometers, TonoLab and TonoPen XL, in detecting physiological or pharmacological changes of intraocular pressure (IOP) in mouse eyes, was assessed by comparison with a microneedle method. MATERIAL AND METHODS C57BL6 mice, bred under the 12-hr light and dark cycle over 2 weeks, were used. Under systemic anesthesia, mouse eyes were cannulated by a microneedle connected to a transducer and a water reservoir. We manipulated the intracameral pressure by… CONTINUE READING

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