The efficacy and use of finasteride in women: a systematic review

  title={The efficacy and use of finasteride in women: a systematic review},
  author={Allison C Hu and Lance W. Chapman and Natasha Atanaskova Mesinkovska},
  journal={International Journal of Dermatology},
Physicians are beginning to use finasteride as treatment for hair loss, hirsutism, and various other dermatologic conditions in women. However, the reported efficacy and use of finasteride in the female population varies widely. The purpose of this study is therefore to better define the efficacy and use of finasteride in women and identify research gaps that require further investigation. 
Finasteride and Its Potential for the Treatment of Female Pattern Hair Loss: Evidence to Date
This review aims to provide novel therapeutic options including topical finasteride and dutasteride, a new generation 5-ARI, for the treatment of FPHL.
Antiandrogen therapy in hidradenitis suppurativa: finasteride for females
The response to and perception of finasteride therapy in a diverse cohort of women with HS is described.
Topical finasteride for the treatment of male androgenetic alopecia and female pattern hair loss: a review of the current literature
Topical finasteride is a promising therapeutic option that aims to decrease complications caused by oral administration and is emphasize the importance of continued research for the establishment of a novel therapeutic agent.
Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients.
Topical finasteride 0.5% in combination with minoxidil 2% could represent a valid therapeutic option for the treatment of postmenopausal FPHL, showing higher efficacy than topical 17α-estradiol with minxidil2% both at 6-month and 12- to 18-month follow-up.
Post-finasteride syndrome: An emerging clinical problem
Nonsurgical hair restoration treatment.
Noninvasive treatment options for patterned hair loss with a focus on minoxidil, finasteride, dutasterides, spironolactone, low-level laser therapy (LLLT), platelet-rich plasma (PRP), microneedling, and oral supplements are discussed.
Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris
Recognizing the preliminary evidence, more peer-reviewed studies on topical antiandrogen treatments for AGA and acne vulgaris are necessary before definitive recommendations can be made regarding efficacy and safety, and there is also a critical need to include more women in study populations for these treatments.
Androgenetic Alopecia: Clinical Treatment
Androgenetic alopecia (AGA) affects predisposed men and women and is characterized by nonscarring progressive miniaturization of the hair follicle accompanied by shortening of the anagen phase,
Is idiopathic hirsutism idiopathic?


5 mg/day finasteride treatment for normoandrogenic Asian women with female pattern hair loss
  • J. Yeon, J. Jung, C. Huh
  • Medicine
    Journal of the European Academy of Dermatology and Venereology : JEADV
  • 2011
Clinical efficacy offinasteride in treating FPHL is still in controversy, but there is a tendency to high dose finasteride, which is more effective than lower dose.
Finasteride in the treatment of female pattern (androgenic) alopecia: a case report and review of the literature.
A 44-year-old woman with biopsy-proven female androgenic alopecia (FAGA) who was nonresponsive to topical minoxidil is described, who was introduced to oral finasteride 1.25 mg daily and showed a remarkable reduction in hair shedding and increased hair regrowth without any reported side effects.
Finasteride Treatment of Hair Loss in Women
Although objective evidence of efficacy is limited, finasteride may be considered for treatment of female pattern hair loss in patients who fail topical minoxidil treatment, and treatment is contraindicated in pregnancy, due to known teratogenicity.
Finasteride cream in hirsutism.
  • K. J. Lucas
  • Medicine
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
  • 2001
Topically applied finasteride significantly decreased hair growth and thickness, and no adverse effects were noted in this study of women with facial hirsutism.
Therapeutic experience with oral finasteride for androgenetic alopecia in female‐to‐male transgender patients
There are no previous studies of the use of finasteride in transgender men as treatment of AGA, but use of 5‐alpha‐reductase inhibitors are useful as oral treatment of AA in men.
Finasteride treatment of female pattern hair loss.
Sixty-two percent of the patients demonstrated some improvement of their hair loss with the use of finasteride, 2.5 mg/d, while taking an oral contraceptive containing drospirenone and ethinyl estradiol, which has an antiandrogenic effect.
Preparation and clinical evaluation of Finastride gel in the treatment of idiopathic Hirsutism
Because of the good absorption through the skin and good solubility of this medicine, the prepared gel formulation applied on the hirsutism area showed a significant decrease in hair growth locally, so finasteride gel is an efficient and harmless therapy in patients with idiopathic hirutism.
Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia.
In postmenopausal women with AGA, finasteride 1 mg/day taken for 12 months did not not increase hair growth or slow the progression of hair thinning.
Effect of finasteride in idiopathic hirsutism
Data demonstrate that 5α-reductase inhibition may be an effective treatment in women suffering from idiopathic hirsutism, and this approach may be attractive due to the absence of adverse reactions, although the necessity of an adequate contraception should be kept in mind.