The efficacy and toxicity of VAD in the treatment of myeloma and related disorders.

@article{Sheehan1986TheEA,
  title={The efficacy and toxicity of VAD in the treatment of myeloma and related disorders.},
  author={Timothy Sheehan and Molly S. Judge and Albert C. E. Parker},
  journal={Scandinavian journal of haematology},
  year={1986},
  volume={37 5},
  pages={425-8}
}
Impressive results have recently been reported in 29 cases of advanced refractory myeloma treated with 4-d infusions of Vincristine and Adriamycin (VAD). We report our own experience with this protocol in 13 cases of myeloma and related lymphoproliferative disorders. In 2 of these cases, VAD was used as first line treatment. Objective responses were seen in two-thirds of cases and the major complication of therapy was infection, predominantly bacterial in nature. 

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