The efficacy and safety of nine South African medicinal plants in controlling Bacillus anthracis Sterne vaccine strain

@article{Elisha2015TheEA,
  title={The efficacy and safety of nine South African medicinal plants in controlling Bacillus anthracis Sterne vaccine strain},
  author={Ishaku Leo Elisha and Jean Paul Dzoyem and Francien Susanna Botha and Jacobus Nicolaas Eloff},
  journal={BMC Complementary and Alternative Medicine},
  year={2015},
  volume={16}
}
BackgroundAnthrax is a zoonotic disease caused by Bacillus anthracis, a Gram-positive spore-forming bacterium. The presence of the bacteria and the toxins in the blood of infected hosts trigger a cascade of pathological events leading to death. Nine medicinal plants with good activities against other bacteria were selected to determine their in vitro antibacterial activity against Bacillus anthracis Sterne strain. The cytotoxicity of the extracts on Vero kidney cells was also determined… 
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IN VITRO ANTIBACTERIAL, ANTIOXIDANT, CYTOGENOTOXIC AND NUTRITIONAL VALUE OF ALOE BARBADENSIS MILL. (ASPHODELACEAE)
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    Journal of Microbiology, Biotechnology and Food Sciences
  • 2020
TLDR
The results of the biological activities of AB root is an indication of its potential use in drug development for the management of infectious diseases and other related ailments.
Phytochemical Composition, Proximate Analysis and Antimicrobial Screening of the Methanolic Extract of Diospyros mespiliformis Hochst ex a. Dc (ebenaceae)
TLDR
Preliminary screening of the methanolic leaf extract of D. mespiliformis was carried out for its phytochemical and proximate constituents in addition to investigating its antimicrobial activity against four bacteria species, showing broad spectrum anti microbial activity in a dose dependent manner.
Common Garlic (Allium sativum L.) has Potent Anti-Bacillus anthracis Activity
TLDR
Garlic (Allium sativum L.) extract was identified as the most promising candidate with bactericidal activity against B. anthracis and was assessed for its thermostability, stability under pH extremes encountered in the gastrointestinal tract, and potential antagonistic interaction with bile salts as well as the FDA-approved antibiotics used for anthrax control.
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