The efficacy and safety of inhaled fluticasone propionate/salmeterol and ipratropium/albuterol for the treatment of chronic obstructive pulmonary disease: an eight-week, multicenter, randomized, double-blind, double-dummy, parallel-group study.

@article{Make2005TheEA,
  title={The efficacy and safety of inhaled fluticasone propionate/salmeterol and ipratropium/albuterol for the treatment of chronic obstructive pulmonary disease: an eight-week, multicenter, randomized, double-blind, double-dummy, parallel-group study.},
  author={Barry J. Make and Nicola Alexander Hanania and Richard L Zuwallack and Christopher J Kalberg and A. J. J. Emmett and Christy P Brown and Katharine Knobil},
  journal={Clinical therapeutics},
  year={2005},
  volume={27 5},
  pages={531-42}
}
BACKGROUND The pathology of chronic obstructive pulmonary disease (COPD) includes both obstructive and inflammatory components. OBJECTIVE The aim of this study was to confirm the findings of a previous study that compared the efficacy of a combination of 2 short-acting bronchodilators with the use of an inhaled corticosteroid and a long-acting beta-agonist in the treatment of COPD. METHODS We conducted an 8-week, multicenter, randomized, double-blind, double-dummy, parallel-group study of… CONTINUE READING

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Salmeterol/fluticasone combination in the treatment of COPD

International journal of chronic obstructive pulmonary disease • 2006
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