The efficacy and dosage effect of corticosteroids for the prevention of atrial fibrillation after cardiac surgery: a systematic review.

@article{Marik2009TheEA,
  title={The efficacy and dosage effect of corticosteroids for the prevention of atrial fibrillation after cardiac surgery: a systematic review.},
  author={Paul Ellis Marik and Robert E. Fromm},
  journal={Journal of critical care},
  year={2009},
  volume={24 3},
  pages={458-63}
}
BACKGROUND Atrial fibrillation (AF) complicates up to 60% of patients after cardiac surgery. Current prophylactic measures are inadequate. Corticosteroids down-regulate activation of the proinflammatory response (including C-reactive protein) after cardiopulmonary bypass and have been suggested to reduce the risk of postoperative AF. OBJECTIVE The goal of this meta-analysis was to determine (i) the efficacy of corticosteroids in preventing AF after cardiac surgery and (ii) the impact of… CONTINUE READING
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