The effects of zolpidem treatment and withdrawal on the in vitro expression of recombinant α1β2γ2s GABAA receptors expressed in HEK 293 cells

@article{Vlaini2010TheEO,
  title={The effects of zolpidem treatment and withdrawal on the in vitro expression of recombinant α1β2γ2s GABAA receptors expressed in HEK 293 cells},
  author={Josipa Vlaini{\'c} and Maja Jazvin{\vs}{\'c}ak Jembrek and Dubravka {\vS}vob {\vS}trac and Danka Peri{\vc}i{\'c}},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2010},
  volume={382},
  pages={201-212}
}
Zolpidem, a widely used hypnotic drug which acts through benzodiazepine binding sites, is a positive allosteric modulator of gamma-aminobutyric acid (GABA) action with preferential affinity for GABAA receptors containing α1 subunit. The pharmacological profile of zolpidem is different from that of classical benzodiazepines. The aim of this study was to find… CONTINUE READING