The effects of vitamin E in ovalbumin-sensitized guinea pigs.

@article{Kilic2003TheEO,
  title={The effects of vitamin E in ovalbumin-sensitized guinea pigs.},
  author={Fatma Sultan Kilic and Kevser Erol},
  journal={Methods and findings in experimental and clinical pharmacology},
  year={2003},
  volume={25 1},
  pages={
          27-31
        }
}
It has been suggested that epithelium destruction, mucus secretion, edema and bronchoconstriction may play a role in asthma pathogenesis. Additionally, histamine, serotonine, leukotrienes and other mediators are released and free oxygen radicals are produced during bronchoconstriction. We studied the role of antioxidants on the treatment of asthma by testing alpha-tocopherol (vitamin E; 5, 25, 50 and 100 mg/kg/day i.p.), a scavenger of oxygen radicals, on male Guinea pigs. The animals were… CONTINUE READING