The effects of vitamin D supplementation on indices of glycemic control in Iranian diabetics: A systematic review and meta-analysis.

@article{Sahebi2019TheEO,
  title={The effects of vitamin D supplementation on indices of glycemic control in Iranian diabetics: A systematic review and meta-analysis.},
  author={Reza Sahebi and Majid Rezayi and Maryam Emadzadeh and Maryam Salehi and Maryam Tayefi and Seyed Mostafa Parizadeh and Negin Behboodi and Azam Rastgar-Moghadam and Jasmin Kharazmi Khorassani and Sara Kharazmi Khorassani and Akbar Mohammadi and Gordon A. Ferns and Majid Ghayour Mobarhan},
  journal={Complementary therapies in clinical practice},
  year={2019},
  volume={34},
  pages={
          294-304
        }
}

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Introduction: Studies have revealed the association between vitamin D deficiency and changes in blood glucose and insulin levels as well as sensitivity of the target tissues to insulin. Objective: In
Effect of vitamin D on insulin resistance and anthropometric parameters in Type 2 diabetes; a randomized double-blind clinical trial
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The present data is not convincing and further studies with large sample sizes are needed to show the definite effect of injection of vitamin D on control of diabetes and its risk.
Effects of vitamin D supplementation on metabolic indices and hs-CRP levels in gestational diabetes mellitus patients: a randomized, double-blinded, placebo-controlled clinical trial
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In GDM patients, vitamin D supplementation improved FG and HbA1c but had no significant effects on lipid profile or hs-CRP.
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The results showed that vitamin D may have a beneficial effect on the control of glycemic profiles and oxidative stress in T2DM patients.
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It seems that vitamin D supplementation has beneficial effects on glucose homeostasis and can increases insulin sensitivity in diabetic 2 patients.
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TLDR
The data showed significant improvements in serum FPG, insulin and in HOMA-IR after treatment with vitamin D, suggested that vitamin D supplementation could reduce insulin resistance in T2DM.
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