The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients.

Abstract

We hypothesized that inadequate oxygenation of peripheral tissues may be unrecognized in critically ill patients and may worsen their prognosis. To test this hypothesis, we measured oxygen delivery to tissues, oxygen uptake, and the extraction ratio (uptake/delivery) before and during a 30-minute infusion of a vasodilator, prostacyclin (5 ng per kilogram of… (More)

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Cite this paper

@article{Bihari1987TheEO, title={The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients.}, author={David J Bihari and M. N. Smithies and Alexander E. S. Gimson and J Tinker}, journal={The New England journal of medicine}, year={1987}, volume={317 7}, pages={397-403} }