The effects of various anions and cations on the regulation of pyruvate dehydrogenase complex activity from pig kidney cortex.

Abstract

The activity of pyruvate dehydrogenase complex (PDC) purified from pig kidney cortex was found to be affected by various uni- and bi-valent ions. At a constant strength of 0.13 M at pH 7.8, K+, Na+, Cl-, HCO3- and HPO4(2-) had significant effects on the activity of PDC: Na+, K+ and HPO4(2-) stimulated, but HCO3- and Cl- inhibited. The stimulatory effect of… (More)

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@article{Pawelczyk1988TheEO, title={The effects of various anions and cations on the regulation of pyruvate dehydrogenase complex activity from pig kidney cortex.}, author={Tadeusz Pawelczyk and Richard A Easom and Merle S. Olson}, journal={The Biochemical journal}, year={1988}, volume={253 3}, pages={819-25} }