The effects of vanadium treatment on bone in diabetic and non-diabetic rats.

@article{Facchini2006TheEO,
  title={The effects of vanadium treatment on bone in diabetic and non-diabetic rats.},
  author={Donatella Facchini and Violet G. Yuen and Mary L. Battell and John Hugh McNeill and Marc D. Grynpas},
  journal={Bone},
  year={2006},
  volume={38 3},
  pages={368-77}
}
Vanadium-based drugs lower glucose by enhancing the effects of insulin. Oral vanadium drugs are being tested for the treatment of diabetes. Vanadium accumulates in bone, though it is not known if incorporated vanadium affects bone quality. Nine- to 12-month-old control and streptozotocin-induced diabetic female Wistar rats were given bis(ethylmaltolato)oxovanadium(IV) (BEOV), a vanadium-based anti-diabetic drug, in drinking water for 12 weeks. Non-diabetic rats received 0, 0.25 or 0.75 mg/ml… CONTINUE READING
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