The effects of three PSO genes on induced mutagenesis : a novel class of mutationally defective yeast.

@article{Cassier1980TheEO,
  title={The effects of three PSO genes on induced mutagenesis : a novel class of mutationally defective yeast.},
  author={Claude Cassier and Roland Chanet and Jo{\~a}o Antonio P{\^e}gas Henriques and Ethel Moustacchi},
  journal={Genetics},
  year={1980},
  volume={96 4},
  pages={841-57}
}
Reverse and forward mutation, induced by photoaddition of 8-methoxypsoralen (8-MOP) and 3-carbethoxypsoralen (3-CPs) or ultraviolet light (UV), are reduced in three pso mutants of Saccharomyces cerevisiae. The pso1-1 strain exhibits a lower frequency of spontaneous reversion (anti-mutator) and is almost entirely unaffected by the three agents in both the haploid and diploid states. The pso2-1 strain demonstrates very reduced frequencies of 8-MOP and 3-CPs plus 365 nm radiation-induced mutations… CONTINUE READING

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Photochemistry and photobiology of psoralens

F. W. STAKL
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