The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat

@article{Cryan1997TheEO,
  title={The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat},
  author={John F. Cryan and Anna M Redmond and John P Kelly and Brian E. Leonard},
  journal={European Neuropsychopharmacology},
  year={1997},
  volume={7},
  pages={109-114}
}

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TLDR
It would appear that flesinoxan should be a useful compound in the clinical management of anxiety after being examined under a procedure that has proved to be a reliable and sensitive method for detecting novel anxiolytic drugs believed to produce their effects at the 5-HT 1A receptor subtype.

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The observations suggested that flesinoxan is an antidepressant agent and that it may be of particular value in some difficult, treatment-resistant depressions.

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The present results are in favour of a 5-HT1A mechanism for the discriminative stimulus of flesinoxan and consistent with the results of previous drug discrimination studies with fles inoxan.

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