The effects of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities.

@article{ElKattan2001TheEO,
  title={The effects of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities.},
  author={Ayman El-Kattan and Charles Asbill and Natalia P. Kim and Bozena Michniak},
  journal={International journal of pharmaceutics},
  year={2001},
  volume={215 1-2},
  pages={229-40}
}
Four model drugs were selected based on their lipophilicity denoted as log P (nicardipine hydrochloride log P -0.99 +/- 0.1, hydrocortisone log P 1.43 +/- 0.47, carbamazepine log P 2.67 +/- 0.38, and tamoxifen log P 7.87 +/- 0.75). The enhancing activities of four terpene enhancers (fenchone log P 2.13 +/- 0.30, thymol log P 3.28 +/- 0.20, D-limonene log P… CONTINUE READING