The effects of tadalafil on renal ischemia reperfusion injury: an experimental study.

@article{Gasanov2011TheEO,
  title={The effects of tadalafil on renal ischemia reperfusion injury: an experimental study.},
  author={Feyzul Gasanov and Berna Aytaç and Hakan Vuruşkan},
  journal={Bosnian journal of basic medical sciences},
  year={2011},
  volume={11 3},
  pages={158-62}
}
Many pharmacological agents were investigated for the prevention of renal ischemic reperfusion (I/R) injury as well as the phosphodiesterase (PDE) inhibitors. The aim of the study was to examine the possible renoprotective effect of a member in this family, tadalafil (Td) on I/R injury. Thirty-six Spraque Dawley rats were allocated to six groups as; control, sham, ischemia (I), ischemia/reperfusion (I/R), Td pretreatment ischemia (Td/I) and Td pretreatment ischemia/reperfusion (Td/IR) groups… CONTINUE READING