The effects of spatial inhomogeneities on flow through the endothelial surface layer.

@article{Leiderman2008TheEO,
  title={The effects of spatial inhomogeneities on flow through the endothelial surface layer.},
  author={Karin Leiderman and Laura A. Miller and Aaron L. Fogelson},
  journal={Journal of theoretical biology},
  year={2008},
  volume={252 2},
  pages={313-25}
}
Flow through the endothelial surface layer (the glycocalyx and adsorbed plasma proteins) plays an important but poorly understood role in cell signaling through a process known as mechanotransduction. Characterizing the flow rates and shear stresses throughout this layer is critical for understanding how flow-induced ionic currents, deformations of transmembrane proteins, and the convection of extracellular molecules signal biochemical events within the cell, including cytoskeletal… CONTINUE READING
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