The effects of some benzoic acid derivatives on polymorphonuclear leukocyte accumulation in vivo.

@article{Killackey1985TheEO,
  title={The effects of some benzoic acid derivatives on polymorphonuclear leukocyte accumulation in vivo.},
  author={J. J. Killackey and B. A. Killackey and Richard B. Philp},
  journal={International journal of immunopharmacology},
  year={1985},
  volume={7 5},
  pages={
          671-6
        }
}
Previous studies, aimed at establishing a relationship between the inhibition of prostaglandin (PG) biosynthesis and the suppression of carrageenin-induced rat paw edema, indicated that, in a series of acetylsalicylic acid (ASA)-like compounds, there is not a good correlation between ability to inhibit platelet PG biosynthesis and anti-inflammatory activity. Some of the compounds tested had good anti-edema properties compared to ASA, but did not inhibit platelet lysate conversion of 14C… Expand
Cyclic nucleotide phosphodiesterase inhibition by a benzoic acid derivative
TLDR
It is proposed that the potent anti-inflammatory effects of 3-MP, which differ from those of ASA, are mediated through the inhibition of the cyclic nucleotide PDE system. Expand
Liquid-phase catalytic oxidation of p-acyl-substituted toluenes with oxygen
A method based on the liquid-phase oxidation of p-acyl-substituted toluenes has been developed for the synthesis of p-acyl-substituted benzoic acids. It is possible s to recycle the unreactedExpand

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