The effects of ropivacaine hydrochloride on coagulation and fibrinolysis. An assessment using thromboelastography.

@article{Porter1999TheEO,
  title={The effects of ropivacaine hydrochloride on coagulation and fibrinolysis. An assessment using thromboelastography.},
  author={J. S. Porter and Jenny McGinley and Brendan O'Hare and George Shorten},
  journal={Anaesthesia},
  year={1999},
  volume={54 9},
  pages={902-6}
}
Amide local anaesthetics impair coagulation by inhibition of platelet function and enhanced fibrinolysis. The potential therefore exists that the presence of amide local anaesthetics in the epidural space could contribute to the therapeutic failure of an epidural autologous blood patch. Ropivacaine is an aminoamide local anaesthetic increasingly used for… CONTINUE READING