The effects of ristocetin and von Willebrand factor on platelet electrophoretic mobility.

Abstract

Ristocetin will induce the agglutination of platelets in the presence of von Willebrand factor. In previous studies, an electrostatic mechanism was proposed for this phenomenon wherein first the platelet's surface charge is reduced by the binding of ristocetin and then the von Willebrand factor acts as a bridge between platelets. To test this hypothesis… (More)

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@article{Coller1978TheEO, title={The effects of ristocetin and von Willebrand factor on platelet electrophoretic mobility.}, author={Barry S. Coller}, journal={The Journal of clinical investigation}, year={1978}, volume={61 5}, pages={1168-75} }