The effects of renzapride, a novel prokinetic agent, in diabetic gastroparesis

@article{Mackie1991TheEO,
  title={The effects of renzapride, a novel prokinetic agent, in diabetic gastroparesis},
  author={Alasdair Mackie and Colin M. Ferrington and S. Cowan and Kelvin R. Palmer},
  journal={Alimentary Pharmacology \& Therapeutics},
  year={1991},
  volume={5}
}
Gastric emptying was measured in 9 diabetic patients with autonomic neuropathy (Group 1) and 8 normal controls (Group 2) on 4 occasions after swallowing placebo, 0.5, 1.0 or 2.0 mg of the newly developed prokinetic drug renzapride given double‐blind and in random order. The liquid component of the test meal was labelled with In113m and the solid with Tc99m. Liquid emptying was uni‐exponential. Solid emptying comprised an initial lag phase, followed by a linear component. Following placebo, the… 
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