The effects of regurgitant orifice size, chamber compliance, and systemic vascular resistance on aortic regurgitant velocity slope and pressure half-time.

@article{Griffin1991TheEO,
  title={The effects of regurgitant orifice size, chamber compliance, and systemic vascular resistance on aortic regurgitant velocity slope and pressure half-time.},
  author={Brian P. Griffin and Frank Flachskampf and Samuel C. Siu and Arthur E. Weyman and James W. Thomas},
  journal={American heart journal},
  year={1991},
  volume={122 4 Pt 1},
  pages={1049-56}
}
The determinants of the aortic regurgitant velocity profile have been investigated using computer and in vitro simulations in which regurgitant orifice area, ventricular and aortic compliance, and systemic vascular resistance could be independently varied. In the study, regurgitant fraction was altered, either by changing the size of the regurgitant orifice or by holding the regurgitant orifice constant and changing chamber compliance or systemic vascular resistance. Upon increasing regurgitant… CONTINUE READING