The effects of psychotomimetic drugs on primary suggestibility

  title={The effects of psychotomimetic drugs on primary suggestibility},
  author={B. M. Jr. Sjoberg and Leo E. Hollister},
SummaryMescaline, LSD-25, psilocybin, and a combination of these three drugs were each administered in moderate doses at 7-day intervals to 24 volunteer subjects according to a latin square design. Primary suggestibility, that type closely related to hypnosis, was measured both before and 2 hrs following each administration of drugs, using the 17-item Stanford Suggestibility Scale. A Trance Indicator Score was also obtained, representing both behavioral observations and subjective reports… 


  • D. Nichols
  • Psychology, Biology
    Pharmacological Reviews
  • 2016
Blood oxygen level–dependent functional magnetic resonance imaging and magnetoencephalography have been employed for in vivo brain imaging in humans after administration of a psychedelic, and results indicate that intravenously administered psilocybin and LSD produce decreases in oscillatory power in areas of the brain’s default mode network.

Lysergic acid diethylamide: a drug of ‘use’?

The receptor pharmacology, mechanism of action, effects and adverse effects of LSD on the normal body system are described, and its addictive potentials and the chances of developing tolerance are highlighted.

Enhancement of suggestibility and imaginative ability with nitrous oxide

Imaginative suggestibility and imaginative ability (imagery vividness) were both elevated in the nitrous oxide condition, and possible explanations of these findings are discussed.

The neurochemistry of hypnotic suggestion

This work draws on pharmacological, genotyping, neuroimaging, and electrophysiological research to synthesize current knowledge regarding the potential role of multiple widely-studied neurochemicals in response to hypnotic suggestion.

Psychedelics and Psychotherapy.

A framework for understanding why psychedelics are likely to be effective with very diverse types of psychotherapies is created and some common conceptual vocabulary is provided that can be used to frame therapeutic psychedelic effects beyond the confines of any one specific modality.

Will psilocybin lose its magic in the clinical setting?

The difficulties that may arise as psilocybin emerges from the research setting, which may hamper its progress towards becoming a licenced medication, are considered.

Culture, context, and ethics in the therapeutic use of hallucinogens: Psychedelics as active super-placebos?

Following decades of prohibition and widespread concern about their mind-altering properties, there is increasing public, scholarly, and clinical interest in the therapeutic potential of psychedelic

New Psychoactive Substances (NPS), Psychedelic Experiences and Dissociation: Clinical and Clinical Pharmacological Issues

Although the complex link between NPS and psychiatric illnesses is yet to be fully understood, NPS misuse is now a significant clinical issue and an increasing challenge for clinicians working in both mental health and emergency departments.

Psychedelics and hypnosis: Commonalities and therapeutic implications

Harnessing the power of suggestion to modulate response to psychedelics could enhance their therapeutic efficacy by helping to increase the likelihood of positive responses, including mystical-type experiences.

Human hallucinogen research: guidelines for safety

The unique history of human hallucinogens research is discussed, the risks of hallucinogen administration and safeguards for minimizing these risks are reviewed, and carefully conducted research may inform the treatment of psychiatric disorders, and may lead to advances in basic science.




  • L. Alexander
  • Psychology
    Annals of the New York Academy of Sciences
  • 1957
T tranquilizing medication, particularly with chlorpromazine, is most effective in the manic state since, as I have pointed out, that condition is most directly power-driven toward excitation by tension anxiety and is a state in which important ego functions are relatively preserved.

States of Heightened Suggestibility: Narcosis

(I) Introduction.—The present paper reports the results of certain experiments carried out in an attempt to obtain information on the increase in suggestibility which is often said to follow the


In this short book, which is the first of its kind to appear, the authors have described the various physical treatments for psychiatric disorders which have been developed in the last 20 years, and conclude that the somatic approach is only capable of improving the instrument that is in the authors' hands; psychotherapy rmay have something to say of the aim towards which it is directed.

The Use of LSD in Psychotherapy

The use of LSD in Psychotherapy and the Psychedelic Experience and Beyond, pp. 52-62, is described.

Experimental design in psychological research.