The effects of portacaval shunting and portacaval transposition on serun IgG levels in the rat.

@article{Benjamin1976TheEO,
  title={The effects of portacaval shunting and portacaval transposition on serun IgG levels in the rat.},
  author={Irving S. Benjamin and Carolyn J. Ryan and A L Mclay and Claydell H Horne and Leslie Harold Blumgart},
  journal={Gastroenterology},
  year={1976},
  volume={70 5 PT.1},
  pages={
          661-4
        }
}
In rats subjected to end-to-side portacaval shunt and to portacaval transposition, serum IgG levels rose progressively by approximately 100% over a 5-week period. During the same period, sham-operated control animals showed only the increase expected with age. Rats with a portacaval shunt showed a greater fall in body weight and liver weight than did those with a portacaval transposition, and also showed a greater fall in levels of liver-synthesized proteins. Serum enzyme levels were markedly… CONTINUE READING