The effects of polyamines on cardiac protein biosynthesis.

Abstract

Putrescine, spermine, and spermidine were able to stimulate cell-free protein biosynthesis at low Mg++ ion concentrations. The addition of polyamines to the perfusate of an isolated perfused rat heart preparation caused an increased rate of [14C]phenylalanine incorporation into myocardial protein. Spermine increased the uptake of alpha-aminoisobutyric acid… (More)

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