The effects of phosphate, pH, and AS volume on RBCs stored in saline-adenine-glucose-mannitol solutions.

@article{Hess2000TheEO,
  title={The effects of phosphate, pH, and AS volume on RBCs stored in saline-adenine-glucose-mannitol solutions.},
  author={John R Hess and Lloyd E Lippert and C P Derse-Anthony and Heather R Hill and Cindy K Oliver and Neeta Rugg and Allen D. Knapp and Jennifer F Gormas and Tibor J. Greenwalt},
  journal={Transfusion},
  year={2000},
  volume={40 8},
  pages={1000-6}
}
BACKGROUND RBC ATP concentrations are the most important correlate of RBC viability. Tests were performed to determine whether increased AS volume, pH, and phosphate content increased stored RBC ATP concentrations. STUDY DESIGN AND METHODS In three studies, packed RBCs were pooled in groups of 3 or 4 units and realiquoted as combined units to reduce intradonor differences. Pooled units were stored in the licensed ASs, AS-1 or AS-5, which contain saline, adenine, glucose, and mannitol (SAGM… CONTINUE READING
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