The effects of peptide-based modification of alginate on left ventricular remodeling and function after myocardial infarction.

@article{TsurGang2009TheEO,
  title={The effects of peptide-based modification of alginate on left ventricular remodeling and function after myocardial infarction.},
  author={Orna Tsur-Gang and Emil Ruvinov and Natalie Landa and Radka Holbova and Micha Feinberg and Jonathan Leor and Smadar Cohen},
  journal={Biomaterials},
  year={2009},
  volume={30 2},
  pages={189-95}
}
Adverse cardiac remodeling and dysfunction after myocardial infarction (MI) is associated with (BioLineRx, BL-1040 myocardial implant) excessive damage to the extracellular matrix. Biomaterials, such as the in situ-forming alginate hydrogel, provide temporary support and attenuate these processes. Here, we tested the effects of decorating alginate biomaterial with cell adhesion peptides, containing the sequences RGD and YIGSR, or a non-specific peptide (RGE), in terms of therapeutic outcome… CONTINUE READING

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