The effects of pegylated interferon-α and ribavirin on liver and serum concentrations of activin-A and follistatin in normal Wistar rat: a preliminary report

@inproceedings{Refaat2015TheEO,
  title={The effects of pegylated interferon-α and ribavirin on liver and serum concentrations of activin-A and follistatin in normal Wistar rat: a preliminary report},
  author={Bassem Refaat and Adel Galal Ahmed El-Shemi and Ahmed Mohammed Ashshi},
  booktitle={BMC Research Notes},
  year={2015}
}
Activin-A and follistatin regulate the liver and the immune system. To measure the effects of treatment with pegylated-interferon-α (Peg-IFN-α) and ribavirin on the concentrations of mature activin-A and follistatin in serum and liver tissue homogenates in rats. A total of 28 male Wistar rats were divided equally into four groups as follow: ‘Control group’ (n = 7), ‘PEG only group’ consisted of those that only received a weekly injection of Peg-IFN-α (6 µg/rat) for 4 weeks, ‘RBV only group… CONTINUE READING

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