The effects of oxidative stress induced by prolonged low-dose diesel exhaust particle exposure on the generation of allergic airway inflammation differ between BALB/c and C57BL/6 mice.

@article{Li2009TheEO,
  title={The effects of oxidative stress induced by prolonged low-dose diesel exhaust particle exposure on the generation of allergic airway inflammation differ between BALB/c and C57BL/6 mice.},
  author={Y Li and Hajime Takizawa and Arata Azuma and Tadashi Kohyama and Yasuhiro Yamauchi and Tomoyuki Kawada and Shoji Kudoh and Isamu Sugawara},
  journal={Immunopharmacology and immunotoxicology},
  year={2009},
  volume={31 2},
  pages={230-7}
}
We have recently reported that airway inflammatory responses to the oxidative stress induced by prolonged low-dose diesel exhaust particle (DEP) exposure differ markedly between BALB/c and C57BL/6 mice. In the present study, the effects of genetic differences in the response to prolonged low-dose DEP exposure on the generation of ovalbumin-induced allergic airway inflammation were further explored using the same mouse strains. In BALB/c mice, eosinophils and mucous goblet cells in… CONTINUE READING