The effects of ondansetron and granisetron on electrocardiography in children receiving chemotherapy for acute leukemia.

@article{Buyukavci2005TheEO,
  title={The effects of ondansetron and granisetron on electrocardiography in children receiving chemotherapy for acute leukemia.},
  author={Mustafa Buyukavci and Haşim Olgun and Naci Ceviz},
  journal={American journal of clinical oncology},
  year={2005},
  volume={28 2},
  pages={
          201-4
        }
}
5-HT3 receptor antagonists, including granisetron and ondansetron, are widely used in the prophylactic treatment of chemotherapy-induced nausea and vomiting. Although the cardiac safety of granisetron and ondansetron has been investigated in several adult studies, there is no report investigating the effects of those agents on electrocardiography (ECG) in children. The effects of intravenously infused (over 30 seconds) 0.1 mg/kg ondansetron and 40 microg/kg granisetron on ECG were assessed in… CONTINUE READING

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