The effects of nonsteroidal anti-inflammatory drugs on renal function: experimental studies in animals.

@article{Zambraski1995TheEO,
  title={The effects of nonsteroidal anti-inflammatory drugs on renal function: experimental studies in animals.},
  author={Edward J. Zambraski},
  journal={Seminars in nephrology},
  year={1995},
  volume={15 3},
  pages={205-13}
}
Studies in various experimental animal models have been invaluable in delineating the physiological and pathophysiological conditions under which renal prostaglandin (PG) synthesis is a major determinant of renal function; conditions in which the inhibition of renal PG synthesis by the administration of a nonsteroidal anti-inflammatory drug (NSAID) will significantly alter kidney function. This article presents the initial schema or concept that under certain well-defined conditions or disease… CONTINUE READING
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