The effects of nociceptin peptide (N/OFQ)-receptor (NOP) system activation in the airways.

Abstract

The heptadecapeptide nociceptin/orphanin FQ (N/OFQ) is the endogenous ligand for the N/OFQ peptide (NOP) receptor. It is cleaved from a larger precursor identified as prepronociceptin (ppN/OFQ). NOP is a member of the seven transmembrane-spanning G-protein coupled receptor (GPCR) family. ppN/OFQ and NOP receptors are widely distributed in different human… (More)
DOI: 10.1016/j.peptides.2012.10.008

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Cite this paper

@article{Singh2013TheEO, title={The effects of nociceptin peptide (N/OFQ)-receptor (NOP) system activation in the airways.}, author={Shailendra Singh and Nikol Sullo and Bruno D'Agostino and Christopher Edward Brightling and David Lambert}, journal={Peptides}, year={2013}, volume={39}, pages={36-46} }