The effects of nicotine on conditioning, extinction, and reinstatement in humans.

@article{Palmisano2016TheEO,
  title={The effects of nicotine on conditioning, extinction, and reinstatement in humans.},
  author={Alexandra N. Palmisano and Eleanor C Hudd and Courtney M McQuade and Harriet de Wit and Robert S. Astur},
  journal={Addictive behaviors},
  year={2016},
  volume={77},
  pages={
          51-58
        }
}
Nicotine has been shown to enhance the reinforcement and reward-responsiveness of non-nicotine stimuli. To determine whether nicotine enhances the strength of conditioning to context, undergraduate participants with varying levels of nicotine dependence were recruited for a two-day study and tested on a virtual reality (VR) conditioned place preference (CPP) paradigm. On day one, participants explored two virtual rooms where they received multiple pairings of M&M rewards in one room and no… CONTINUE READING
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