The effects of neuronal induction on gene expression profile in bone marrow stromal cells (BMSC)--a preliminary study using microarray analysis.

@article{Yamaguchi2006TheEO,
  title={The effects of neuronal induction on gene expression profile in bone marrow stromal cells (BMSC)--a preliminary study using microarray analysis.},
  author={Satoshi Yamaguchi and Satoshi Kuroda and Hiroyuki Kobayashi and Hideo Shichinohe and Shunsuke Yano and Katzutoshi Hida and Kazuyoshi Shinpo and Seiji Kikuchi and Yoshinobu K Iwasaki},
  journal={Brain research},
  year={2006},
  volume={1087 1},
  pages={15-27}
}
Bone marrow stromal cells (BMSC) have been anticipated as a donor for cell type for transplantation therapy in various neurological disorders. However, their neurogenic capacity still remains undetermined. In this study, we aimed to clarify whether in vitro chemical treatment promotes their neuronal differentiation on the level of gene expression. Mice BMSC were cultured with medium supplemented with DMSO, retinoic acid, and basic fibroblast growth factor, and their morphology and expression of… CONTINUE READING

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