The effects of naloxone on the neural control of the urinary bladder of the cat

@article{Roppolo1983TheEO,
  title={The effects of naloxone on the neural control of the urinary bladder of the cat},
  author={James R. Roppolo and A. J. Cadamy M. G. Booth and W. C. de Groat},
  journal={Brain Research},
  year={1983},
  volume={264},
  pages={355-358}
}
Naloxone in doses ranging from 0.5 to 512 micrograms/kg i.v., enhanced reflex contractions of the urinary bladder of the cat. At the lowest doses (threshold, 0.5-5 micrograms/kg) the drug increased the frequency of spontaneous bladder contractions. In large doses (10-100 micrograms/kg) the drug produced an initial tonic contraction of bladder lasting 15-40 min followed by a period of high frequency rhythmic activity. Multiunit firing in parasympathetic postganglionic nerves on the surface of… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

AB260. Role of µ, κ, and δ opioid receptors in tibial inhibition of bladder overactivity in cats

The Journal of pharmacology and experimental therapeutics • 2015
View 2 Excerpts

Propranolol, but not naloxone, enhances spinal reflex bladder activity and reduces pudendal inhibition in cats.

American journal of physiology. Regulatory, integrative and comparative physiology • 2015
View 4 Excerpts

Neurophysiology of micturition and continence in women

International Urogynecology Journal • 1997
View 1 Excerpt

Similar Papers

Loading similar papers…