The effects of nadolol on various cardiac tissues in normoxia, and on atrial muscle in simulated ischaemia.

Abstract

Nadolol, a non-selective beta-blocker with a long duration of action, reportedly is devoid of membrane stabilizing action. Since such action is augmented by ischaemic conditions, it was of interest to investigate whether, in simulated ischaemia, a direct membrane effect of nadolol might be revealed. We have confirmed that in normoxia nadolol had no effects… (More)

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