The effects of muscle length on intracellular calcium transients in mammalian cardiac muscle.

@article{Allen1982TheEO,
  title={The effects of muscle length on intracellular calcium transients in mammalian cardiac muscle.},
  author={David G. Allen and Satoshi Kurihara},
  journal={The Journal of physiology},
  year={1982},
  volume={327},
  pages={79-94}
}
1. The calcium-sensitive photoprotein aequorin was micro-injected into cells of rat and cat ventricular muscles. The resulting light emission is a function of intracellular free calcium concentration ([Ca2+]i). The transient increases in [Ca2+]i that accompany contraction were monitored. 2. After an increase in muscle length, the developed tension increased immediately and then showed a slow increase over a period of minutes. The peak [Ca2+]i in each contraction was initially unchanged after an… CONTINUE READING
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