The effects of multivitamins on cognitive performance: a systematic review and meta-analysis.

@article{Grima2012TheEO,
  title={The effects of multivitamins on cognitive performance: a systematic review and meta-analysis.},
  author={Natalie A. Grima and Matthew P. Pase and Helen Macpherson and Andrew Pipingas},
  journal={Journal of Alzheimer's disease : JAD},
  year={2012},
  volume={29 3},
  pages={
          561-9
        }
}
Complementary medicine use is becoming increasingly popular with multivitamins being the most commonly used vitamin supplement. Although adequate vitamin and nutrient concentrations are necessary for optimal health and cognitive functioning, there is no scientific consensus as to whether multivitamin use prevents cognitive decline or improves mental functioning. The aim of the present study was to determine if multivitamins can be used efficaciously to improve cognitive abilities. A systematic… 

Multivitamin-multimineral supplementation and mortality: a meta-analysis of randomized controlled trials.

No effect of multivitamin-multimineral treatment on all-cause mortality was observed across all studies, and no statistical evidence of heterogeneity or publication bias was observed.

Effects of cocoa extract and a multivitamin on cognitive function: A randomized clinical trial.

INTRODUCTION Dietary supplements are touted for cognitive protection, but supporting evidence is mixed. COSMOS-Mind tested whether daily administration of cocoa extract (containing 500 mg/day

The effects of chronic multivitamin supplementation on neurocognition in the elderly

Findings indicate supplementation with a combined multivitamin, mineral and herbal formula may benefit memory performance in elderly at risk of cognitive decline and growing evidence suggests that dietary supplementation with selected micronutrients and nutraceuticals may have the potential to improve cognition in older adults.

Long-Term Multivitamin Supplementation and Cognitive Function in Men

In male physicians aged 65 years or older, long-term use of a daily multivitamin did not provide cognitive benefits and doses of vitamins may be too low or the population may beToo well-nourished to benefit from a multiv vitamin.

Recent developments in multivitamin/mineral research.

New evidence from 2010 onward is provided addressing the committee's primary concerns about multivitamin/mineral research in regard to improving public health and includes several recent studies that may be of interest to future committees indicating the potential benefits of these supplements on improving the cognitive performance and mental well-being of healthy populations.

Acute mood but not cognitive improvements following administration of a single multivitamin and mineral supplement in healthy women aged 50 and above: a randomised controlled trial

It was demonstrated that the MVMH supplement improved overall DASS mood ratings; however, the most prominent effects appeared to be a reduction in ratings of perceived mental stress.

Acute Effects of Different Multivitamin Mineral Preparations with and without Guaraná on Mood, Cognitive Performance and Functional Brain Activation

Previous work has identified the positive effects of the acute administration of a multivitamin-guaraná preparation during an effortful executive/working memory task. Here, we aimed to differentiate

Improvement in Cognition Following Double-Blind Randomized Micronutrient Interventions in the General Population

Evidence suggests that sub-optimal micronutrient intake may have a negative effect on cognition across the lifespan.

Broad-spectrum micronutrient formulas for the treatment of psychiatric symptoms: a systematic review

Despite positive preliminary findings, there are less data available to support efficacy of micronutrient formulas in treating bipolar disorder, attention deficit-hyperactivity disorder and substance abuse/dependence and no clinical trials have been done with clinically depressed or anxious patient samples, psychosis or eating disorders.
...

References

SHOWING 1-10 OF 33 REFERENCES

Multiple micronutrient supplementation for improving cognitive performance in children: systematic review of randomized controlled trials.

Multiple micronutrient supplementation may be associated with a marginal increase in fluid intelligence and academic performance in healthy schoolchildren but not with crystallized intelligence.

The influence of multivitamins on cognitive function and mood in the elderly

Although multivitamin supplementation in healthy, elderly volunteers had little effect on cognitive function or mood, it is possible that supplementation over longer periods of time and/or in volunteers with poorer nutritional status may prove beneficial.

Effect of multivitamin and multimineral supplementation on cognitive function in men and women aged 65 years and over: a randomised controlled trial

The results provide no evidence for a beneficial effect of daily multivitamin and multimineral supplements on these domains of cognitive function in community-living people over 65 years, but the possibility of beneficial effects in older people and those at greater risk of nutritional deficiency deserves further attention.

Effects of high-dose B vitamin complex with vitamin C and minerals on subjective mood and performance in healthy males

Healthy members of the general population may benefit from augmented levels of vitamins/minerals via direct dietary supplementation, as vitamin/mineral supplementation led to improved ratings of stress, mental health and vigour and improved cognitive performance during intense mental processing.

A vitamin/nutriceutical formulation improves memory and cognitive performance in community-dwelling adults without dementia.

Findings support the benefit of nutritional supplements for cognitive performance and suggest that additional supplementation may be required for the elderly.

Provision of multiple rather than two or fewer micronutrients more effectively improves growth and other outcomes in micronutrient-deficient children and adults.

There is some evidence that MMN supplementation improves CD4 counts and HIV-related morbidity and mortality in adults, and overall there is evidence that outcomes are better than when providing < or =2 MN.

A controlled trial of homocysteine lowering and cognitive performance.

The hypothesis that homocysteine lowering with B vitamins improves cognitive performance is not supported, and the results of this trial do not support this hypothesis.

Anti‐oxidant vitamins and mental performance of the elderly

The results showed little effect of supplementation on mental performance and few associations between plasma levels of the vitamins and mental functioning, in contrast to results from assessment of mood, intelligence and cognitive failure.

Multivitamin-multimineral supplements: who uses them?

  • C. Rock
  • Medicine
    The American journal of clinical nutrition
  • 2007
MVMM use contributes a considerable proportion of nutrient intakes in the United States and may contribute to risk of excessive intakes, among adults with a history of breast or prostate cancer, and usage rates for dietary supplements in general and MVMMs are considerably higher.