The effects of metformin with lifestyle therapy in polycystic ovary syndrome: a randomized double-blind study.

Abstract

OBJECTIVE To determine if the combination of lifestyle (caloric restriction and exercise) and metformin (MET) would be superior to lifestyle and placebo (PBO) in improving the polycystic ovary syndrome (PCOS) phenotype. DESIGN Double-blind randomized 6-month trial of MET versus PBO. SETTING Two academic medical centers. PATIENT(S) One hundred fourteen… (More)
DOI: 10.1016/j.fertnstert.2010.12.002

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