The effects of mechanical vibration on cardiac morphogenesis in the stage 14 chick embryo.


The primitive cardiac loop of the stage 14 (Hamburger and Hamilton) chick embryo was subjected to brief vibratory stimuli that resulted in a broad spectrum of cardiovascular malformations. During the 17th day of incubation, both survival and anomaly rates were evaluated. Compared with control embryos (92%), vibration elicited mortality (75%) that was… (More)